Navigation auf uzh.ch
Navigation auf uzh.ch
N-linked glycosylation is a common class of glycosylation encountered in all eukaryotes as well as in Archaea and some bacteria. In eukaryotes, the assembly of N-glycans follows a complex sequence of events spanning the ER and the Golgi apparatus. The ER pathway is strongly conserved within eukaryotes, but the Golgi pathway shows extensive differences between fungi, plants and animals. In addition to carrying epitopes involved in protein-protein interactions in the extracellular space, N-glycans also fulfill important roles in the maturation and intracellular trafficking of glycoproteins.
