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The Cellular Oxygen Physiology Group is exploring the molecular mechanisms and therapeutical consequences of cellular adaptation to changing ambient oxygen conditions like found at high altitude, sites of inflammation, fibrotic tissue remodeling or the tumor microenvironment.
Functions of the PHD and FIH oxygen sensors
Functional interplay between PHD oxygen sensors and HIF transcrioption factors
Mechanisms of renal oxygen sensing and signaling and pathophysiological conditions