Publications (since 2010)

ZORA Publication List
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Publications
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Twenty-eight days of exposure to 3454 m increases mitochondrial volume density in human skeletal muscle. Journal of Physiology, 594(5):1151-1166.
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Mechanisms of Endothelial Homoglobin Toxicity. 2016, University of Zurich, Faculty of Science.
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Renal tubular disorders of electrolyte regulation in children. In: Avner, E D; et al. Pediatric Nephrology / 7th edition. New York: Springer, 1201-1271.
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Impaired Lysosomal Function Underlies Monoclonal Light Chain-Associated Renal Fanconi Syndrome. Journal of the American Society of Nephrology (JASN), 27(7):2049-2061.
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Genome-wide Association Studies Identify Genetic Loci Associated with Albuminuria in Diabetes. Diabetes, 65(3):803-817.
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Calcineurin Inhibitors Downregulate HNF-1β and May Affect the Outcome of HNF1B Patients After Renal Transplantation. Transplantation, 100(9):1970-1978.
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Albuminuria and tolvaptan in autosomal-dominant polycystic kidney disease: results of the TEMPO 3:4 Trial. Nephrology, Dialysis, Transplantation, 31(11):1887-1894.
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NFκB-sensitive Orai1 expression in the regulation of FGF23 release. Journal of Molecular Medicine, 94(5):557-566.
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Long wavelength multiphoton excitation is advantageous for intravital kidney imaging. Kidney International, 89(3):712-719.
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Acetazolamide Attenuates Lithium-Induced Nephrogenic Diabetes Insipidus. Journal of the American Society of Nephrology (JASN), 27(7):2082-2091.
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Loss of function mutation of the Slc38a3 glutamine transporter reveals its critical role for amino acid metabolism in the liver, brain, and kidney. Pflügers Archiv : European Journal of Physiology, 468(2):213-227.
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Autosomal-recessive mutations in SLC34A1 encoding sodium-phosphate cotransporter 2A cause idiopathic infantile hypercalcemia. Journal of the American Society of Nephrology (JASN), 27(2):604-614.
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Targeted delivery of CCR2 antagonist to activated pulmonary endothelium prevents metastasis. Journal of Controlled Release, 220(PtA):341-347.
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Cystic Kidney Disease. In: Turner, Neil. Oxford Textbook of Clinical Nephrology. Oxford: Oxford University Press, 111-112.
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Erythropoietin does not reduce plasma lactate, H(+) , and K(+) during intense exercise. Scandinavian Journal of Medicine & Science in Sports, 25(6):e566-e575.
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The 1000 Genomes Project: Welcome to a new world. Peritoneal Dialysis International, 35(7):676-677.
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Endothelial CCR2 Promotes Pulmonary Metastasis. 2015, University of Zurich, Faculty of Science.
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Nuclear heparanase-1 activity suppresses melanoma progression via its DNA-binding affinity. Oncogene, 34:5832-5842.
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Hemoglobin mass and intravascular volume kinetics during and after exposure to 3,454-m altitude. Journal of Applied Physiology, 119(10):1194-1201.
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Rab-GAP TBC1D4 (AS160) is dispensable for the renal control of sodium and water homeostasis but regulates GLUT4 in mouse kidney. American Journal of Physiology : Renal Physiology, 309(9):F779-F790.
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The Effect of Exercise Training on the Energetic Cost of Cycling. Sports Medicine, 45(11):1603-1618.
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Enhanced Performance after Repeated Sprint Training in Hypoxia: False or Reality?. Medicine and Science in Sports and Exercise, 47(11):2483.
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Uromodulin, kidney function, cardiovascular disease, and mortality. Kidney International, 88(5):944-946.
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Clinically relevant concentrations of lidocaine and ropivacaine inhibit TNFα-induced invasion of lung adenocarcinoma cells in vitro by blocking the activation of Akt and focal adhesion kinase. British Journal of Anaesthesia, 115(5):784-791.
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Amino acid handling in the organism, lessons from mouse and human studies. 2015, University of Zurich, Faculty of Science.
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Limitations to oxygen transport and utilization during sprint exercise in humans: evidence for a functional reserve in muscle O2 diffusing capacity. Journal of Physiology, 593(20):4649-4664.
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Haematological rather than skeletal muscle adaptations contribute to the increase in peak oxygen uptake induced by moderate endurance training. Journal of Physiology, 593(20):4677-4688.
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How astrocyte networks may contribute to cerebral metabolite clearance. Scientific Reports, 5(15024):online.
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Endurance Training and V˙O2max: Role of Maximal Cardiac Output and Oxygen Extraction. Medicine and Science in Sports and Exercise, 47(10):2024-2033.
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Interstitial Fibrosis Restricts Osmotic Water Transport in Encapsulating Peritoneal Sclerosis. Journal of the American Society of Nephrology (JASN), 26(10):2521-2533.
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Autosomal dominant tubulointerstitial kidney disease: diagnosis, classification, and management—A KDIGO consensus report. Kidney International, 88(4):676-683.
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Chloride transporters and receptor-mediated endocytosis in the renal proximal tubule. Journal of Physiology, 593(18):4151-4164.
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The pH-sensing receptor OGR1 improves barrier function of epithelial cells and inhibits migration in an acidic environment. American Journal Of Physiology. Gastrointestinal And Liver Physiology, 309(6):475-490.
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CrossTalk opposing view: Diffusion limitation of O2 from microvessels into muscle does not contribute to the limitation of V̇O2 max. Journal of Physiology, 593(17):3759-3761.
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Rebuttal from Carsten Lundby and David Montero. Journal of Physiology, 593(17):3765.
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The ugly duckling of urinary acidification: what is the contribution of the thick ascending limb of the loop of Henle to urinary acidification?. American Journal of Physiology : Renal Physiology, 309(5):431-433.
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Heat training increases exercise capacity in hot but not in temperate conditions: a mechanistic counter-balanced cross-over study. American Journal of Physiology - Heart and Circulatory Physiology, 309(5):H750-H761.
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Water and solute transport across the peritoneal membrane. Current Opinion in Nephrology and Hypertension, 24(5):434-443.
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The Regulation of Fibroblast Growth Factor 23 in Autosomal Dominant Polycystic Kidney Disease. 2015, University of Zurich, Faculty of Science.
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Biomarkers in Autosomal Dominant Polycystic Kidney Disease. 2015, University of Zurich, Faculty of Medicine.
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CCL2-CCR2 signaling in disease pathogenesis. Endocrine, Metabolic & Immune Disorders Drug Targets, 15(2):105-118.
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Altitude training causes haematological fluctuations with relevance for the Athlete Biological Passport. Drug Testing and Analysis, 7(8):655-662.
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Cerebrovascular reactivity is increased with acclimatization to 3,454 m altitude. Journal of Cerebral Blood Flow and Metabolism, 35(8):1323-1330.
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The SAM domain of ANKS6 has different interacting partners and mutations can induce different cystic phenotypes. Kidney International, 88(2):299-310.
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Molecular physiology of water balance. New England Journal of Medicine, 373(2):196.
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Performance enhancement: What are the physiological limits?. Physiology, 30(4):282-292.
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Factors influencing success of clinical genome sequencing across a broad spectrum of disorders. Nature Genetics, 47(7):717-726.